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使用 BioLine™ CMOS 相机,提升您的成像能力

2022年5月4日 作者: IDEX Health & Science

向下滚动,观看我们关于从 CCD 升级到 CMOS 的网络研讨会

 

为广泛的生命科学成像应用选择相机可能是一项具有挑战性的任务。传感器在成像系统中扮演着重要的角色,因此需要深入了解仪器的规格和产品参数。在弱光环境中使用荧光和化学发光的凝胶和印迹成像系统,需要更高的分辨率和灵敏度,才能生成出版质量的图像和数据集。当以很长的曝光时间获取图像时,牢靠且经济的冷却能力对于降低暗散粒噪声非常重要。

在目标为大数据捕获的细胞高内涵成像中,大视野(FOV) 和更高的速度将是好的相机功能。优化高内涵成像系统时,要考虑的其他特性是大动态范围和宽光谱灵敏度(高 QE)。

一些用于快的检测生物标志物的数字免疫分析平台将单分子荧光检测与流式细胞仪相结合。可以提供单分子检测能力,检测限显著提高。如果在延长的曝光时间和宽动态范围内没有更高的灵敏度,这样的改进是不可能的。

考虑到这些需求,BioLine™ CMOS 平台由 Finger Lakes Instrumentation (FLI) 在 IDEX Health & Science 旗下开发。它旨在提供一系列具有各种像素密度和格式的索尼传感器,适用于从凝胶文档成像到 DNA 测序和空间转录组学的生命科学应用。我们在不同生命科学应用领域的光学和系统工程师团队,可以通过提高成像性能,帮助您的系统更上一层楼。作为光学和流控的生产商,我们提供完整的工艺、组件和功能组合,从源到传感器系统到单个光源、滤光片、光学模块和相机解决方案。

IDEX 相机可实现多重生物标志物检测系统成像

案例研究:具有宽动态范围的高灵敏度 IDEX 相机是多重生物标志物检测系统获得牢靠且可重现结果的关键组件。

希望更换过时 CCD 相机的生命科学仪器制造商可以使用该系列相机。由于在速度、读取噪声和成本方面的优势,CMOS 在许多应用中已好于 CCD 。CMOS 的一个典型缺点是较高的暗电流噪声。因此,长时间曝光应用的热控制(能够从弱光环境中收集足够的光子)对于高质量图像至关重要。BioLine CMOS 相机建立在牢靠、成熟的 TE 冷却工艺上,使用户即使在低光应用中也能获得更高的 SNR 图像。我们的 IDEX Health & Science 团队可以使用您的系统参数提供详细的 SNR 分析,从而帮助您对合适的 CMOS 候选者做出明智的决定。

需要从 CCD 过渡到 CMOS?

观看我们近期的网络研讨会,重点关注如何利用 CMOS 的优势,以及如何在选择下一台相机时做出数据驱动的决策。

立即了解,如何使用 BioLine 相机提升您的成像能力。

了解更多 BIOLINE 相机

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